Olafur Eliasson’s tears used to make human cheese

Bacteria from personalities including artist Olafur Eliasson, curator Hans Ulrich Obrist and chef Michael Pollan have been used to make human cheese as part of an exhibition about synthetic biology in Dublin.

Cheeses made with human bacteria recreate the smell of armpits or feet
Cheese made from chef Michael Pollan’s belly button bacteria

American scientist Christina Agapakis and Norwegian scent expert Sissel Tolaas collected bacteria from Obrist’s nose, Eliasson’s tears and Pollan’s belly button and used them to make the artisanal dairy products.

“We are presenting a set of cheeses made using bacteria from the human body,” Agapakis told Dezeen. “Everybody has a unique and diverse set of bacteria living on their skin that can be amplified using techniques from microbiology and grown directly in milk to form and flavour each cheese.”

The project, called Selfmade, features eleven cheeses in total, made from bacterial cultures harvested from the skin of artists, scientists, anthropologists, and cheese makers using sterile cotton swabs that were sent to the donors.

Cheeses made with human bacteria recreate the smell of armpits or feet
Cheese made of microbes from cheesemaker Seana Doughty’s mouth.

The cheeses each smell, and taste, of the body odour of the donor, Agapakis said.

“It’s no surprise that sometimes cheese odours and body odours are similar,” she explained. “But when we started working together we were surprised by how not only do cheese and smelly body parts like feet share similar odour molecules but also have similar microbial populations.”

Cheeses made with human bacteria recreate the smell of armpits or feet
Cheese made from microbiologist Ben Wolfe’s toe microbes

The project aims to demonstrate how living organisms that exist in the body also exist in food, and vice versa, and how microbiology can be used to harness and manipulate such organisms to create synthetic microbes with enhanced properties.

Cheeses made with human bacteria recreate the smell of armpits or feet
Cheese made from food writer Michael Pollan’s belly button bacteria

“Despite [their] chemical and biological similarities, there are obviously very different cultural and emotional responses to stinky cheese and stinky feet,” said Agapakis. “By making cheese directly from the microbes on the body, we want to highlight these bacterial connections as well as to question and potentially expand the role of both odours and microbes in our lives.”

“Nobody will eat these cheeses, but we hope that the cheese can inspire new conversations about our relationship to the body and to our bacteria.”

Cheeses made with human bacteria recreate the smell of armpits or feet
Cheese made from microbiologist Ben Wolfe’s toe microbes

The cheeses form part of the Grow Your Own – Life After Nature exhibition at the Science Gallery in Dublin.

The show also features curator Alexandra Daisy Ginsberg’s proposal to create synthetic creatures to help solve environmental problems and a concept for humans giving birth to animals such as dolphins that they could then eat.

Cheeses made with human bacteria recreate the smell of armpits or feet
Cheese made from food writer Michael Pollan’s belly button bacteria

In their artistic statement about the project, Agapakis and Tolaas say they hope to draw attention to the importance and potential of bacteria and to overcome a cultural fear of micro-organisms.

Cheeses made with human bacteria recreate the smell of armpits or feet
Cheese made of microbes from cheesemaker Seana Doughty’s mouth.

“Can knowledge and tolerance of bacterial cultures in our food improve tolerance of the bacteria on our bodies?” they write. “How do humans cultivate and value bacterial cultures on cheeses and fermented foods? How will synthetic biology change with a better understanding of how species of bacteria work together in nature as opposed to the pure cultures of the lab?”

Cheeses made with human bacteria recreate the smell of armpits or feet
Cheese made from microbiologist Ben Wolfe’s toe microbes

Grow Your Own – Life After Nature is at the Science Gallery in Dublin until 19 January 2014.

Here’s some more info from Agapakis and Tolaas:


Selfmade

The growing awareness of human microbial ecology and its influence on health is leading to wider understanding of the body as a superorganism; a collection of human and microbial cells that interact in numerous and unexpected ways. In this paradigm, notions of self and other, and of health and disease, are shifting to accommodate more ecological concepts of diversity and symbiosis.

Selfmade is a series of ‘microbial sketches’, portraits reflecting an individual’s microbial landscape in a unique cheese. Each cheese is crafted from starter cultures sampled from the skin of a different person. Isolated microbial strains were identified and characterised using microbiological techniques and 16S ribosomal RNA sequencing. Like the human body, each cheese has a unique set of microbes that metabolically shape a unique odour.

Cheese odours were sampled and characterised using headspace gas chromatography-mass spectrometry analysis, a technique used to identify and/or quantify volatile organic compounds present in a sample. A short film documenting the process of cheesemaking, along with interviews of the bacterial donors accompanies the cheese display and the data from microbiological and odour analysis. Visitors to the gallery are exposed to the diversity of life in their food and bodies, and a diversity of visions for future synthetic biologies.

Cheeses made with human bacteria recreate the smell of armpits or feet
Refrigerated cheeses

This project explores possibilities for a relational synthetic biology through the practices of cheesemaking. Cheesemaking involves a complex coordination of microbial life, promoting the growth of beneficial Lactobacillus strains that protect milk from more dangerous spoilage and the ecologies of microbes on the rind that create the prized flavours of different cheese varieties.

Those involved with synthetic biology are intent on transforming microbes into the useful machines of a new bioeconomy. In the short term, this is accomplished by isolating engineered strains and limiting microbial interactions in stainless steel reactors. However, the appeal of potential medium-term applications in the production of foods, environmental biosensors, or ‘smart’ living therapeutics demonstrates the power of thinking beyond the bioreactor.

Such approaches require addressing ecological concerns about the safety and complexity of interactions with other organisms, highlighting the need for a more relational synthetic biology. Understanding the biological networks inside cells as well as the networks of organisms, regulatory systems, economic structures, and cultural practices that shape the life of an engineered organism in the world will be crucial to the development of synthetic biologies in the long term.

Artist’s Statement

We not only live in a biological world surrounded by rich communities of microorganisms, but in a cultural world that emphasises total antisepsis. The intersection of our interests in smell and microbial communities led us to focus on cheese as a ‘model organism’. Many of the stinkiest cheeses are hosts to species of bacteria closely related to the bacteria responsible for the characteristic smells of human armpits or feet.

Can knowledge and tolerance of bacterial cultures in our food improve tolerance of the bacteria on our bodies? How do humans cultivate and value bacterial cultures on cheeses and fermented foods? How will synthetic biology change with a better understanding of how species of bacteria work together in nature as opposed to the pure cultures of the lab?”

The post Olafur Eliasson’s tears used
to make human cheese
appeared first on Dezeen.

I Wanna Deliver A Dolphin… concept for humans giving birth to their food by Ai Hasegawa

This synthetic biology project by designer Ai Hasegawa imagines that a woman could gestate and give birth to a baby from another species, in this case a dolphin, before eating it (+ movie).

I Wanna Deliver A Dolphin by Ai Hasegawa

I Wanna Deliver a Dolphin… was developed by Ai Hasegawa to tackle food shortages and satisfy maternal instincts as the human population burgeons by giving women the option to become surrogates for endangered animals hunted for food.

Hasegawa proposes synthesising a placenta that could support an animal in a human womb.

“This project approaches the problem of human reproduction in an age of overcrowding, overdevelopment and environmental crisis,” Hasegawa said. “With potential food shortages and a population of nearly seven billion people, would a woman consider incubating and giving birth to an endangered species such as a shark, tuna or dolphin?”

I Wanna Deliver A Dolphin by Ai Hasegawa

The designer also questions whether someone would feel differently about eating a delicacy having personally carried and nurtured it.

“Would raising this animal as a child change its value so drastically that we would be unable to consume it because it would be imbued with the love of motherhood?” asked Hasegawa.

As a case study for the concept Hasegawa chose the Maui’s dolphin, one of the world’s smallest and most rare species of dolphin that has been critically endangered as a consequence of human fishing.

I Wanna Deliver A Dolphin by Ai Hasegawa

A Maui’s dolphin is roughly the same size as a human baby and is regarded as highly intelligent.

For a woman to gestate a dolphin, Hasegawa proposes biologically modifying a placenta to prevent the passage of antibodies from mother to baby that attack non-human cells.

“The placenta originates from the baby’s side, which in this case is a dolphin, and not from the human side,” said Hasegawa. “This avoids the ethical and legal difficulties associated with reproductive research involving human eggs.”

The “dolp-human” placenta would be altered to distinguish between mammal and non-mammal cells, rather than human and other cells, so the foetus would escape attack from the antibodies.

I Wanna Deliver A Dolphin by Ai Hasegawa

After birth, the mother would have to administer fat-rich synthesised milk to the baby to build it’s immune system, which a dolphin would naturally get from its mother’s milk rather than via the placenta.

Hasegawa first showed the idea at the Royal College of Art graduate show earlier this year and the project is currently on display as part of Grow Your Own… Life After Nature, an exhibition of synthetic biology projects at the Science Gallery in Dublin.

The exhibition also features synthetic living creatures that could be released into the wild to save endangered species and a proposal to use animal cells to print new types of organs for preventing heart attacks or strokes.

Here’s the information from Ai Hasegawa:


I Wanna Deliver A Dolphin…

Humans are genetically predisposed to raise children as a way of passing on their genes to the next generation. For some, the struggle to raise a child in decent conditions is becoming harder due to gross overpopulation and an increasingly strained global environment.

This project approaches the problem of human reproduction in an age of overcrowding, overdevelopment and environmental crisis. With potential food shortages and a population of nearly seven billion people, would a woman consider incubating and giving birth to an endangered species such as a shark, tuna or dolphin? This project introduces the argument for giving birth to our food to satisfy our demands for nutrition and childbirth, and discusses some of the technical details of how this might be possible.

Would raising this animal as a child change its value so drastically that we would be unable to consume it because it would be imbued with the love of motherhood? The Maui’s dolphin has been chosen as the ideal “baby” for this piece. It is one of the world’s rarest and smallest dolphins, classified critically endangered by the International Union for Conservation’s Red List of Threatened Species (version 2.3) because of the side effects of fishing activity by humans, its size (which closely matches the size of a human baby), and its high intelligence level and communication abilities.

I Wanna Deliver a Dolphin… imagines a point in the future, where humans will help this species by the advanced technology of synthetic biology. A “dolp-human placenta” that allows a human female to deliver a dolphin is created, and thus humans can become a surrogate mother to endangered species. Furthermore, gourmets would be able to enjoy the luxury of eating a rare animal: an animal made by their own body, raising questions of the ownership of rare animal life, and life itself.

I Wanna Deliver A Dolphin by Ai Hasegawa
Diagram of dolphin foetus in a human womb plus explanation – click for larger image

Synthetic Dolp-human Placenta

To make it possible for a human mother to deliver a dolphin from her womb, there is a need to synthesise “The Dolp-human Placenta”. The usual human placenta interacts to pass from mother to baby oxygen, carbon dioxide, nutrients, hormones, antibodies (Immunoglobulin Gamma, IgG) and so on. The Dolp-human placenta blocks the delivery of IgG to the baby.

The placenta originates from the baby’s side, which in this case is a dolphin, and not from the human side. This avoids the ethical and legal difficulties associated with reproductive research involving human eggs.

The decidua is formed by implantation of the egg. Usually, foreign cells in the body (for example from other individuals) are attacked by the immune system, but inside the decidua they are tolerated. However, even though the decidua accepts cells from other individuals, non-human cells would still be attacked. In the dolp-human placenta case, it has been modified to distinguish mammal from non-mammal cells, making it even more tolerant.

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giving birth to their food by Ai Hasegawa
appeared first on Dezeen.